展会邀请 | 福流生物邀您参加ATMP2024第八届先进疗法创新峰会

随着全球范围内学术、医疗、资本与产业的积极参与，ATMP相关在研产品数量呈现爆发式增长。与此同时，该领域也面临着法规监管、工艺开发、商业化生产、出海合作、患者可及性等诸多问题与挑战。为促进来源于中国的高质量研发创新，快速推进先进治疗产品的研发与商业化进程，探索合作新模式，第八届先进疗法创新峰会将于2024年12月19-20日在上海康桥万豪酒店举办。

届时，福流生物将携纳米流式检测仪产品参会，我们诚挚邀请并欢迎各位专家学者莅临3号展位进行交流。

会议信息

时间：2024年12月19-20日

地点：上海康桥万豪酒店

展位信息

报告信息

报告标题

Comprehensive analysis of extracellular vesicles using nano-flow cytometry

单分子纳米流式检测技术在外泌体综合表征中的应用

主讲人

于鑫梅  厦门福流生物科技有限公司（应用工程师）

报告时间

12月20日  9:50-10:15

报告地点

Ballroom B-工程化外泌体与细胞外囊泡，递送及关键技术创新专题

摘要

Nano-sized extracellular vesicles (EVs) released by various cell types play important roles in a plethora of (patho)physiological processes and are increasingly recognized as biomarkers for diseases. Moreover, engineered EVs and EV-inspired liposomes hold great potential as drug delivery vehicles. EVs released from different cell types (and even from a single cell type) are shown to be highly heterogeneous in size and nanostructure, where a specific vesicle subtype could be solely responsible for a particular function. The function of EVs is typically evaluated on RNA level (qPCR) and protein level (ELISA, IF, Western blots). However, these ensemble-averaged techniques could not discern the distinct subset among other abundant EVs. Therefore, a sensitive, specific, and rapid methodology is urgently needed to measure the abundance of these specific markers on EVs at the single-particle level. Flow NanoAnalyzer opens a new avenue for the detection of single EVs, especially for the detection of exosomes—the subset of EVs with size ranging from 30-150 nm. Light scattering is used for the measurement of EV size and size distributions. Fluorescence detection is used to analyze the chemical properties of EVs. Thus, size, concentration, chemical attributes, and biological features on the EVs surface or in cavities can be characterized, and correlated analysis of these attributes can be facilitated at the single-nanoparticle level.

会议日程