发表论文

Author: admin     Date: September 6, 2021

Extracellular Vesicles (Exosomes)

A Versatile Platform for Generating Engineered Extracellular Vesicles with Defined Therapeutic Properties.
Dooley K, McConnell, R. E. et al.
Molecular Therapy, 2021

Characterization of extracellular vesicles and artificial nanoparticles with four orthogonal single-particle analysis platforms.
Mallick E R., Arab, Huang Y.et al.
bioRxiv, 2021

Measuring particle concentration of multimodal synthetic reference materials and extracellular vesicles with orthogonal techniques: Who is up to the challenge?
Vogel R, Savage J, Muzard J, et al.
Journal of Extracellular Vesicles, 2021

Comprehensive evaluation of methods for small extracellular vesicles separation from human plasma, urine and cell culture medium.
Dong L, Zieren R C, et al.
Journal of Extracellular Vesicles, 2021

Establishment of a simplified dichotomic size-exclusion chromatography for isolating extracellular vesicles toward clinical applications.
Jiahui, Guo, et al.
Journal of extracellular vesicles, 2021

NIR-II emissive lateral flow immunoassay for accurate determination of tumor marker in hemolysis.
Chen, Rui, et al.
Sensors and Actuators B: Chemical, 2021

Extracellular Vesicle-Based Coatings Enhance Bioactivity of Titanium Implants—SurfEV
Pansani, T N, Phan T H, Chrzanowski W, et al.
Nanomaterials, 2021

New Multiscale Characterization Methodology for Effective Determination of Isolation–Structure–Function Relationship of Extracellular Vesicles
Phan T H, Divakarla S K, Chrzanowski W, et al.
Frontiers in Bioengineering and Biotechnology, 2021

Synthetic Antigen Presenting cells reveal the diversity and functional specialisation of extracellular vesicles composing the fourth signal of  T cell immunological synapses
L Dustin M, Cespedes P, et al.
bioRxiv, 2021

BATF2 prevents glioblastoma multiforme progression by inhibiting recruitment of myeloid-derived suppressor cells.
Zhang, Xin, et al.
Oncogene, 2021

A magnetic bead-mediated selective adsorption strategy for extracellular vesicle separation and purification.
Fang X., Chen C., Liu B., et al.
Acta Biomaterialia,2021

Extracellular vesicles isolated by size-exclusion chromatography present suitability for RNomics analysis in plasma.
Yang, Y., Wang, Y., Wei, S., et al.
Journal of Translational Medicine,2021

Considerations for MESF-bead based assignment of absolute fluorescence values to nanoparticles and extracellular vesicles by flow cytometry.
Lozano-Andrés, Estefanía, et al.
bioRxiv,2021

Micro/nano-textured hierarchical titanium topography promotes exosome biogenesis and secretion to improve osseointegration.
Zhang Z., Xu R., Yang Y., et al.
biotechnology,2021

Small extracellular vesicles from human adipose-derived mesenchymal stromal cells: a potential promoter of fat graft survival.
Chen A, Tang S, He J, et al.
Stem Cell Research & Therapy,2021

The Role of Small Extracellular Vesicles Derived from Lipopolysaccharide-preconditioned Human Dental Pulp Stem Cells in Dental Pulp Regeneration.
Chen, Wen-Jin, et al.
Journal of Endodontics,2021

Controlled release of MSC-derived small extracellular vesicles by an injectable Diels-Alder crosslinked hyaluronic acid/PEG hydrogel for osteoarthritis improvement.
Yang Y, Zhu Z, Gao R, et al.
Acta Biomaterialia,2021

MicroRNA -370 carried by M2 macrophage-derived exosomes alleviates asthma progression through inhibiting the FGF1/MAPK/STAT1 axis.
Li C, Deng C, Zhou T, et al.
International journal of biological sciences,2021

Neural stem cell-derived exosomes regulate neural stem cell differentiation through miR-9-Hes1 axis.
Yuan P, Ding L, Chen H, et al.
Frontiers in Cell and Developmental Biology,2021

Plasma-derived exosomal ALIX as a novel biomarker for diagnosis and classification of pancreatic cancer.
Yang J, Zhang Y, Gao X, et al.
Frontiers in Oncology,2021

Priming with Toll-Like Receptor 3 Agonist Poly (I: C) Enhances Content of Innate Immune Defense Proteins but not MicroRNAs in Human Mesenchymal Stem Cell-Derived Extracellular Vesicles.
Pierce, Lisa, and Wendy E. Kurata.
Frontiers in Cell and Developmental Biology,2021

Comparison and Investigation of Exosomes Derived from Platelet-Rich Plasma Activated by Different Agonists.
Rui S, Yuan Y, Du C, et al
Cell Transplantation,2021

Synthetic Antigen Presenting cells reveal the diversity and functional specialisation of extracellular vesicles composing the fourth signal of T cell immunological synapses.
Pablo F. ，As J，Lola Fe -Me , et al.
BioRxiv,2021

Platelet Rich Plasma-Derived Exosomal USP15 Promotes Cutaneous Wound Healing via Deubiquitinating EIF4A1.
Xu, Y, Lin Z, He L, et al.
Oxid Med Cell Longev,2021

Extracellular vesicles isolated by size-exclusion chromatography present suitability for RNomics analysis in plasma.
Yang Y, Wang Y, Wei S, et al.
Journal of Translational Medicine,2021

Considerations for MESF-bead based assignment of absolute fluorescence values to nanoparticles and extracellular vesicles by flow cytometry.
Lozano-Andrés, E., Van Den Broeck，et al.
bioRxiv,2021

Amiloride ameliorates muscle wasting in cancer cachexia through inhibiting tumor-derived exosome release.
Zhou, Lin, et al.
Skeletal muscle,2021

Exosomes Derived from Nerve Stem Cells Loaded with FTY720 Promote the Recovery after Spinal Cord Injury in Rats by PTEN/AKT Signal Pathway.
Chen J, Zhang C, Li S, et al.
Journal of Immunology Research,2021

Comparison of The Variability of Small Extracellular Vesicles Derived From Human Liver Cancer Tissues And Cultured From The Tissue Explants Based On A Simple Enrichment Method: Yield, Purity And Molecular Markers.
Chen J, Jiao Z, Mo J,  et al.
Stem Cell Rev Rep,2021

The Role of Small Extracellular Vesicles Derived from Lipopolysaccharide-preconditioned Human Dental Pulp Stem Cells in Dental Pulp Regeneration.
Chen W J, Xie J, Lin X, et al.
Journal of Endodontics,2021

Compositional Features of Distinct Microbiota Base on Serum Extracellular Vesicle Metagenomics Analysis in Moderate to Severe Psoriasis Patients.
Chang C J, Zhang J, Tsai Y L, et al.
Cells,2021

PD-L1 detection on circulating tumor-derived extracellular vesicles (T-EVs) from patients with lung cancer.
Wu F, Gu Y, Kang B, et al.
Translational Lung Cancer Research,2021

Isolation and characterization of extracellular vesicle subpopulations from tissues.
Crescitelli, Rossella, Cecilia Lässer, and Jan Lötvall.
Nature Protocols,2021

Outcome prediction of microdissection testicular sperm extraction based on extracellular vesicles piRNAs.
Chen H, Xie Y, Li Y,  et al.
Journal of Assisted Reproduction and Genetics,2021

Quantification of protein cargo loading into engineered extracellular vesicles at single‐vesicle and single‐molecule resolution.
Silva, A. M, Lázaro‐Ibáñez, et al.
Journal of Extracellular Vesicles,2021

High-Throughput Simultaneous mRNA Profiling Using nCounter Technology Demonstrates That Extracellular Vesicles Contain Different mRNA Transcripts Than Their Parental Prostate Cancer Cells.
Dong, L., Huang, C. Y., Johnson,  et al.
Analytical Chemistry,2021

Scaled preparation of extracellular vesicles from conditioned media.
Staubach, Simon, et al.
Advanced Drug Delivery Reviews,2021

Abnormal expression profile of plasma-derived exosomal microRNAs in patients with treatment-resistant depression.
Li L D, Naveed M, Du Z W, et al.
Human genomics,2021

General and mild modification of food-derived extracellular vesicles for enhanced cell targeting.
Chen C, Sun M, Liu X, et al.
Nanoscale,2021

Opportunities and Pitfalls of Fluorescent Labeling Methodologies for Extracellular Vesicle Profiling on High-Resolution Single-Particle Platforms.
Fortunato D, Mladenović D, Criscuoli M, et al.
International Journal of Molecular Sciences,2021

Comparison of the Variability of Small Extracellular Vesicles Derived from Human Liver Cancer Tissues and Cultured from the Tissue Explants Based on a Simple Enrichment Method.
Chen J, Jiao Z, Mo J, et al.
Stem Cell Reviews and Reports,2021

A Hypercoagulable Hematological Metastasis Breast Cancer Model.
Yang W J, Zhang G L, Cao K X, et al.
BioMed Research International, 2021

Outcome prediction of microdissection testicular sperm extraction based on extracellular vesicles piRNAs.
Chen H, Xie Y, Li Y, et al.
Journal of Assisted Reproduction and Genetics, 2021

Distinct Proteomic Profiling of Plasma Extracellular Vesicles from Moderate-to-Severe Atopic Dermatitis Patients.
Chang C J, Wang H Q, Zhang J, et al.
Clinical, Cosmetic and Investigational Dermatology, 2021

Cardiac microvascular functions improved by MSC-derived exosomes attenuate cardiac fibrosis after ischemia–reperfusion via PDGFR-β modulation.
Wang X, Bai L, Liu X, et al.
International Journal of Cardiology, 2021

Serum exosome-derived biomarkers for the early detection of oral squamous cell carcinoma.
Guo H, Jiang W, Huang S, et al.
Molecular and Cellular Biochemistry, 2021

Periodontal ligament fibroblast-Derived Exosomes Induced by Compressive Force promote macrophage M1 polarization via Yes-Associated Protein.
Zhao M, Ma Q, Zhao Z, et al.
Archives of Oral Biology, 2021

细菌囊泡纯度、浓度及粒径分布的单颗粒水平定量表征.
牛倩；田野；吴明凯；张宇豪；陈晨；颜晓梅*.
分析化学, 2020

高灵敏、宽动态范围纳米流式检测装置的研制及应用.
毛翠萍；林垚；牛倩；薛乘风；颜晓梅*.
分析化学, 2020

尿液细胞外囊泡的单颗粒水平多参数定量表征.
刘海生；袁文理；陈永钰；陈晨；田野；颜晓梅*
分析化学, 2020

Articular chondrocyte-derived extracellular vesicles promote cartilage differentiation of human umbilical cord mesenchymal stem cells by activation of autophagy.
Ma K, Zhu B, Wang Z, et al.
Journal of Nanobiotechnology, 2020

Exosomal miR-100-5p inhibits osteogenesis of BMSCs and angiogenesis of VECs by suppressing BMPR2/Smad1/5/9 signaling pathway.
Yang, Wu, et al.
Stem Cell Res Ther, 2020

MicroRNA-enriched small extracellular vesicles possess odonto-immunomodulatory properties for modulating the immune response of macrophages and promoting odontogenesis.
Zheng J, Kong Y, Hu X, et al.
Stem cell research & therapy,2020

Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Improve Ovarian Function and Proliferation of Premature Ovarian Insufficiency by Regulating the Hippo Signaling Pathway.
Li Z, Zhang M, Zheng J, et al.
Frontiers in Endocrinology,2021

Influence of species and processing parameters on recovery and content of brain tissue-derived extracellular vesicles.
Huang, Yiyao, et al.
Journal of Biomaterials and Tissue Engineering,2020

miR-101 Inhibits AKT/mTOR and Attenuates Oral Cancer Cell Colony Formation and Epithelial-Mesenchymal Transition.
Long, Fei, et al.
Journal of Biomaterials and Tissue Engineering,2020

p53 Inhibits Lung Cancer Proliferation and Invasion by Regulating miR-34a and Epithelial-Mesenchymal Transition Transformation.
Fu, Changyou, et al.
Journal of Biomaterials and Tissue Engineering,2020

Relationships of Alzheimer’s disease and apolipoprotein E genotypes with small RNA and protein cargo of brain tissue extracellular vesicles.
Huang Y, Driedonks T A, Cheng L, et al.
medRxiv,2020

Therapeutic mechanism of human neural stem cell-derived extracellular vesicles against hypoxia-reperfusion injury in vitro.
Liu Q, Tan Y, Qu T, et al.
Life Sciences,2020

Plasma extracellular vesicles detected by Single Molecule array technology as a liquid biopsy for colorectal cancer.
Wei P, Wu F, Kang B, et al.
Journal of extracellular vesicles,2020

Heparanase from triple‑negative breast cancer and platelets acts as an enhancer of metastasis.
Yang, W. J, Zhang, et al.
International Journal of Oncology,2020

The future of Extracellular Vesicles as Theranostics–an ISEV meeting report.
Soekmadji C, Li B, Huang Y, et al.
Journal of Extracellular Vesicles,2020

Mesenchymal stem cell-derived exosomes protect beta cells against hypoxia-induced apoptosis via miR-21 by alleviating ER stress and inhibiting p38 MAPK phosphorylation.
Chen, Jin, et al.
Stem cell research & therapy,2020

Radiation-induced small extracellular vesicles as “carriages” promote tumor antigen release and trigger antitumor immunity.
Lin W, Xu Y, Chen X, et al.
Theranostics,2020

Clinical Significance of Circulating Exosomal PD-L1 and Soluble PD-L1 in Nasal-type NK/T-cell Lymphoma Patients，Receiving VIPD Containing Chemotherapy.
Jiwei Li，Ping Wei，Ye Guo，et al.
Research Square,2020

Technologies and Standardization in Research on Extracellular Vesicles.
Gandham S, Su X, Wood J, et al.
Trends in Biotechnology, 2020

Separation of extracellular vesicles by DNA-directed immunocapturing followed by enzymatic release.
Brambilla D, Sola L, Chiodi, et al.
ChemRixv , 2020

Radiation-induced small extracellular vesicles as “carriages” promote tumor antigen release and trigger antitumor immunity.
Lin W, Xu Y, Chen X, et al.
Theranostics, 2020

Relationships of Alzheimer’s disease and apolipoprotein E genotypes with small RNA and protein cargo of brain tissue extracellular vesicles.
Huang Y, Driedonks T A, Cheng L, et al.
medRxiv, 2020

Extracellular vesicles containing host restriction factor IFITM3 inhibited Zika virus infection of fetuses in pregnant mice through trans-placenta delivery.
Zou X, Yuan M, Zhang T,  et al.
Molecular Therapy, 2020

Plasma extracellular vesicles detected by Single Molecule array technology as a liquid biopsy for colorectal cancer.
Wei P, Wu F, Kang B, et al.
Journal of Extracellular Vesicles, 2020

The future of Extracellular Vesicles as Theranostics– an ISEV meeting report.
Soekmadji C, Li B, Huang Y, et al.
Journal of Extracellular Vesicles, 2020

Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles.
Jiang W, Ma P, Deng L, et al.
Journal of Extracellular Vesicles, 2020

Quality and efficiency assessment of six extracellular vesicle isolation methods by nano-flow cytometry.
Tian Y, Gong M, Hu Y, et al.
Journal of Extracellular Vesicles, 2020

Extracellular Vesicle Delivery of TRAIL Eradicates Resistant Tumor Growth in Combination with CDK Inhibition by Dinaciclib.
Ke C, Hou H., Li J et al.
Cancers, 2020

Extracellular vesicle isolation from human renal cancer tissue.
Zieren R C, Dong L, Pierorazio P M, et al.
Medical Oncology, 2020

Small Extracellular Vesicles From Human Adipose-derived Stem Cells: A Potential Promoter of Keeping Fat Graft Survival.
Chen A, Tang S, He J, et al
Stem Cell Research & Therapy 2020

Therapeutic mechanism of human neural stem cell-derived extracellular vesicles against hypoxia-reperfusion injury in vitro.
Liu Q, Tan Y, Qu T, et al.
Life Sciences, 2020

ESC‐sEVs Rejuvenate Senescent Hippocampal NSCs by Activating Lysosomes to Improve Cognitive Dysfunction in Vascular Dementia.
Hu G, Xia Y, Zhang J, et al.
Advanced Science, 2020

Increased Interleukin-6 Levels in Neuron-Derived Plasma Small Extracellular Vesicles of Subarachnoid Haemorrhage Patients.
Lai N, Yao Y, Yu T, et al.
Research Square, 2020

Small extracellular vesicles secreted by human iPSC-derived MSC enhance angiogenesis through inhibiting STAT3-dependent autophagy in ischemic stroke.
Xia Y, Ling X, Hu G, et al.
Stem Cell Research & Therapy, 2020

The immunomodulatory signature of extracellular vesicles from Cardiosphere-Derived Cells: a proteomic and miRNA profiling.
López E, Marinaro F, de Pedro, et al.
Frontiers in Cell and Developmental Biology, 2020

Small extracellular vesicles derived from embryonic stem cells restore ovarian function of premature ovarian failure through PI3K/AKT signaling pathway.
Liu M, Qiu Y, Xue Z, et al.
Stem Cell Research & Therapy, 2020

Clinical significance of circulating exosomal PD-L1 and soluble PD-L1 in extranodal NK/T-cell lymphoma, nasal-type.
Li J. W, Wei P, Guo, et al.
American journal of cancer research, 2020

Nonmuscle Myosin Heavy Chain ⅡA-Mediated Exosome Release via Regulation of the Rho-Associated Kinase 1/Myosin Light Chains/Actin Pathway.
Lv, Y., Chen, J., Hu, J., et al.
Frontiers in Pharmacology, 2020

Exosomal CA125 as A Promising Biomarker for Ovarian Cancer Diagnosis.
Chen Z, Liang Q, Zeng H, et al.
Journal of Cancer, 2020

Thermosensitive Exosome–Liposome Hybrid Nanoparticle‐Mediated Chemoimmunotherapy for Improved Treatment of Metastatic Peritoneal Cancer.
Lv Q, Cheng L, Lu Y, et al.
Advanced Science, 2020

Exosomal lncRNA RAMP2-AS1 Derived from Chondrosarcoma Cells Promotes Angiogenesis Through miR-2355-5p/VEGFR2 Axis.
Cheng C, Zhang Z, Cheng F, et al.
OncoTargets and therapy, 2020

Serum Exosomal MicroRNA-21, MicroRNA-126, and PTEN Are Novel Biomarkers for Diagnosis of Acute Coronary Syndrome.
Ling H, Guo Z, Shi Y, et al.
Frontiers in Physiology, 2020

Clinical Significance of Circulating Exosomal PD-L1 and Soluble PD-L1 in Nasal-type NK/T-cell Lymphoma Patients, Receiving VIPD Containing Chemotherapy.
Jiwei Li, Ping Wei, Ye Guo, et al.
Research Square, 2020

Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles.
Jiang W, Ma P, Deng L, et al.
Journal of Extracellular Vesicles,2020

Genetically Engineered Cell Membrane Nanovesicles for Oncolytic Adenovirus Delivery: A Versatile Platform for Cancer Virotherapy.
Lv P, Liu X, and Liu G et al.
Nano Letters,2019

Placenta Stem/Stromal Cell–Derived Extracellular Vesicles for Potential Use in Lung Repair.
Kim S Y, Joglekar M V, Hardikar A A, et al.
Proteomics, 2019

Plasma Extracellular Vesicle Long RNA Profiling Identifies a Diagnostic Signature for the Detection of Pancreatic Ductal Adenocarcinoma.
Yu S, Li Y, and Liao Z, et al.
Gut., 2019

Programmable Modulation for Extracellular Vesicles. 
Wany Y, Melvin R, Bemis L, Worrell G, Wang H.
bioRxiv, 2019

Extracellular Vesicles Long RNA Sequencing Reveals Abundant mRNA, circRNA, and lncRNA in Human Blood as Potential Biomarkers for Cancer Diagnosis.
Li Y, Zhao J, and Huang S et al.
Clinical Chemistry, 2019

Extracellular Vesicles Derived from ODN-stimulated Macrophages Transfer and Activate Cdc42 in Recipient Cells and Thereby Increase Cellular Permissiveness to EV Uptake.
Zhang Y, Jin X, and Liang J et al.
Science Advances, 2019

Protein Profiling and Sizing of Extracellular Vesicles from Colorectal Cancer Patients via Flow Cytometry.
Tian Y, Ma L, Gong M, et al.
ACS Nano, 2018

Exosomal transfer of p-STAT3 promotes acquired 5-FU resistance in colorectal cancer cells.
Zhang Q, Liu R X, Chan K W, et al.
Journal of Experimental & Clinical Cancer Research, 2019

Tumor-derived circulating exosomal miR-342-5p and miR-574-5p as promising diagnostic biomarkers for early-stage Lung Adenocarcinoma.
Han Z, Li Y, Zhang J, et al.
International Journal of Medical Sciences, 2020

A Panel of Plasma Exosomal miRNAs as Potential Biomarkers for Differential Diagnosis of Thyroid Nodules.
Liang M, Yu S, Tang S, et al.
Frontiers in Genetics, 2020

Exosomes Derived from Umbilical Cord Mesenchymal Stem Cells Alleviate Mifepristone-Induced Human Endometrial Stromal Cell Injury.
Wang J, Hu R, Xing Q, et al.
Stem Cells International, 2020

PTH Derivative promotes wound healing via synergistic multicellular stimulating and exosomal activities.
Shen Y F, Huang J H, Wang K.Y, et al.
Cell Communication and Signaling, 2020

Articular chondrocyte derived exosomes promote cartilage differentiation of human umbilical cord mesenchymal stem cells by activation of autophagy.
Ma K, Zhu B, Wang Z, et al.
Journal of Nanobiotechnology, 2020

Mesenchymal stem cell-derived exosomes protect beta cells against hypoxia-induced apoptosis via miR-21 by alleviating ER stress and inhibiting p38 MAPK phosphorylation.
Chen J, Chen J, Cheng Y, et al.
Stem cell research & therapy, 2020

Seminal plasma exosomes evoke calcium signal via CatSper channel to regulate human sperm function.
Zhang X, Song D, Zhou W, et al.
bioRxiv, 2020

Exosomes of Antler Mesenchymal Stem Cells Improve Postoperative Cognitive Dysfunction in Cardiopulmonary Bypass Rats through Inhibiting the TLR2/TLR4 Signaling Pathway.
Yang C, Sun S, Zhang Q, et al.
Stem Cells International, 2020

Exosomes isolated from the plasma of remote ischemic conditioning rats improved cardiac function and angiogenesis after myocardial infarction through targeting Hsp70.
Chen Q, Huang M, Wu J, et al.
Aging (Albany NY), 2020

Exosomes from human urine‐derived stem cells enhanced neurogenesis via miR‐26a/HDAC6 axis after ischaemic stroke.
Ling X, Zhang G, Xia Y, et al.
Journal of Cellular and Molecular Medicine, 2020

RNA sequencing of exosomes revealed differentially expressed long noncoding RNAs in early-stage esophageal squamous cell carcinoma and benign esophagitis.
Tian L, Yang L, Zheng W, et al.
Epigenomics, 2020

The expression of small RNAs in exosomes of follicular fluid altered in human polycystic ovarian syndrome.
Hu J, Tang T, Zeng Z, et al.
PeerJ, 2020

Nonmuscle Myosin Heavy Chain ⅡA-Mediated Exosome Release via Regulation of the Rho-Associated Kinase 1/Myosin Light Chains/Actin Pathway.
Lv, Y., Chen, J., Hu, J., et al.
Frontiers in Pharmacology, 2020

Saliva Exosomes-Derived UBE2O Promotes Angiogenesis in Cutaneous Wounds By Targeting SMAD6.
Mi B, Chen L, Xiong Y, et al.
Journal of Nanobiotechnology, 2020

Exosomes from human urine‐derived stem cells enhanced neurogenesis via miR‐26a/HDAC6 axis after ischaemic stroke. 
Ling X, Zhang G, Xia Y, et al.
Journal of Cellular and Molecular Medicine, 2020

Embryonic Stem Cells-Derived Exosomes Endowed with Targeting Properties as Chemotherapeutics Delivery Vehicles for Glioblastoma Therapy.
Zhu Q, Ling X, and Deng Z et al.
Advanced Science, 2019

Exosomal transfer of p-STAT3 promotes acquired 5-FU resistance in colorectal cancer cells.
Kim S Y, Joglekar M V, Hardikar A A, et al.
J Exp Clin Cancer Res, 2019

Renoprotective Effects of Artemisinin and Hydroxychloroquine Combination Therapy on IgA Nephropathy via Suppressing NF-κB Signaling and NLRP3 Inflammasome Activation by Exosomes in Rats.
Bai L, Li J, and Li H et al.
Biochemical Pharmacology, 2019

Urine-Derived Stem Cells Facilitate Endogenous Spermatogenesis Restoration of Busulfan-Induced Nonobstructive Azoospermic Mice by Paracrine Exosomes.
Deng C, Xie Y, and Zhang C et al.
Stem Cells and Development, 2019

Serum Membrane Type 1-Matrix Metalloproteinase (MT1-MMP) mRNA Protected by Exosomes as a Potential Biomarker for Gastric Cancer.
Dong Z, Sun X, Xu J, et al.
International Medical Journal of Experimental and Clinical Research, 2019

Magnetic-Based Microfluidic Device for On-Chip Isolation and Detection of Tumor-Derived Exosomes.
Xu H, Liao C, Zuo P, Liu Z, and Ye B.
Analytical Chemistry, 2018

Multiple antibodies identify glypican-1 associated with exosomes from pancreatic cancer cells and serum from patients with pancreatic cancer.
Dong C, Huang L, Kalluri R. et al.
bioRixv, 2018

Viruses

Quantitative Assessment of the Physical Virus Titer and Purity by Ultrasensitive Flow Virometry.
Yan, Xiaomei, et al.
Angewandte Chemie,2021

Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles.
Jiang W, Ma P, Deng L, et al.
Journal of Extracellular Vesicles, 2020

Genetically Engineered Cell Membrane Nanovesicles for Oncolytic Adenovirus Delivery: A Versatile Platform for Cancer Virotherapy.
Lv P, Liu X, and Liu G et al.
Nano Letters, 2019

Specific detection of live Escherichia coli O157: H7 using tetracysteine-tagged PP01 bacteriophage.
Wu L, Song Y, Luan T, et al.
Biosensors and Bioelectronics, 2016

Label‐Free Analysis of Single Viruses with a Resolution Comparable to That of Electron Microscopy and the Throughput of Flow Cytometry.
Ma L, Zhu S, Tian Y, et al.
Angewandte Chemie, 2016

Nanomedicines (Liposomes)

Single-Particle Characterization of Theranostic Liposomes with Stimulus Sensing and Controlled Drug Release Properties. 
Chen C, Gao K, and Yan X, et al.
Biosensors and Bioelectronics, 2019

Multiparameter Quantification of Liposomal Nanomedicines at the Single-Particle Level by High-Sensitivity Flow Cytometry.
Chen C, Zhu S, Wang S, Zhang W, Cheng Y, and Yan X.
ACS Applied Materials and Interfaces,2017

Light-Scattering Detection below the Level of Single Fluorescent Molecules for High-Resolution Characterization of Functional Nanoparticles.
Zhu S, Ma L, Wang S, et al.
ACS Nano,2014

Analytical techniques for single-liposome characterization.
Chen C, Zhu S, and Yan X et al.
Analytical Methods, 2013

Bacteria

Dual-Fluorescent Bacterial Two-Hybrid System for Quantitative Protein–Protein Interaction Measurement via Flow Cytometry.
Wu L, Su L, Deng M, et al.
Talanta, 2021

Multiplexed detection of bacterial pathogens based on a cocktail of dual-modified phages.
Wu L, Hong X, Luan T, et al.
Analytica Chimica Acta, 2021

Rapid quantification of pathogenic Salmonella Typhimurium and total bacteria in eggs by nano-flow cytometry.
C Mao, C Xue, X Wang, et al.
Talanta, 2020

Label-free detection of bacteria in fruit juice by nano-flow cytometry.
He S, Hong X, Zhang M, et al.
Analytical chemistry,2019

Flow Cytometric Analysis of Nanoscale Biological Particles and Organelles.
Lian H, He S, Chen C, and Yan X.
Annual Review of Analytical Chemistry,2019

Deciphering the antitoxin-regulated bacterial stress response via single-cell analysis.
Wu L, Zhang M, Song Y, et al.
ACS chemical biology,2019

Rapid quantification of live/dead lactic acid bacteria in probiotic products using high-sensitivity flow cytometry.
He S, Huang T, Zhang W, and Yan X et al.
Methods and Applications in Fluorescence, 2017

Flow Cytometric Single-Cell Analysis Enables Quantitative in vivo Detection of Protein-Protein Interactions via Relative Reporter Protein Expression Measurement.
Wu L, Wang X, and Yan X et al.
Analytical Chemistry, 2017

Probing minority population of antibiotic-resistant bacteria.
Huang T, Zheng Y, Yan Y, et al.
Biosensors and Bioelectronics, 2016

Specific detection of live Escherichia coli O157: H7 using tetracysteine-tagged PP01 bacteriophage.
Wu L, Song Y, Luan T, et al.
Biosensors and Bioelectronics, 2016

Rapid detection and enumeration of total bacteria in drinking water and tea beverages using a laboratory-built high-sensitivity flow cytometer.
Yu M, Wu L, Huang T, et al.
Analytical Methods,2015

Trace Detection of Specific Viable Bacteria by Using Tetracysteine-Tagged Bacteriophages.
Wu L, Luan T, and Yan X et al.
Analytical Chemistry, 2014

High-throughput single-cell analysis of low copy number beta-galactosidase by a laboratory-built high-sensitivity flow cytometer.
Yang L, Huang T, and Yan X et al.
Biosensors & Bioelectronics,2013

A covalent reporter of lactamase activity for fluorescent imaging and rapid screening of antibiotic-resistant bacteria.
Shao Q, Zheng Y, Dong X, et al.
Chem.-Eur. J, 2013

Detection and Quantification of Bacterial Autofluorescence at the Single-Cell Level by a Laboratory-Built High-Sensitivity Flow Cytometer.
Yang L, Zhou Y, and Yan X et al.
Analytical Chemistry, 2012

Sensitive and Selective Bacterial Detection Using Tetracysteine-Tagged Phages in Conjunction with Biarsenical Dye.
Wu L, Huang T, and Yan X et al.
Angewandte Chemie International Edition, 2011

Rapid, Absolute, and Simultaneous Quantification of Specific Pathogenic Strain and Total Bacterial Cells Using and Ultrasensitive Dual-Color Flow Cytometer.
Yang L, Wu L, and Yan X et al.
Analytical Chemistry, 2010

Mitochondria

线粒体荧光标记的单颗粒水平高通量评估方法.
韩锦艳，许静怡，张翔，周颖星，陈超翔，颜晓梅*
分析化学,2016

线粒体蛋白质组学研究进展.
许静怡,陈超翔,韩锦艳,杭纬,颜晓梅*
分析化学,2015

Rapid and quantitative in vitro analysis of mitochondrial fusion and its interplay with apoptosis.
Xu J, Su L, Han J, et al.
Talanta, 2021

Quantification of protein copy number in single mitochondria: The Bcl-2 family proteins.
Chen C, Zhang X, Zhang S, et al.
Biosensors & Bioelectronics, 2015

Identification of Mitochondria-Targeting Anticancer Compounds by an in Vitro Strategy.
Zhang X, Zhang S, and Yan X et al.
Analytical Chemistry, 2014

Rapid identification of mitochondria-targeting anticancer compounds by an in vitro strategy.
Zhang, X; Zhang, SY; Zhu, SB，et al.
Anal. Chem, 2014

High-Throughput Multiparameter Analysis of Individual Mitochondria.
Zhang S, Zhu S, and Yan X et al.
Analytical Chemistry, 2012

Nanomaterials

Immunomodulating nano-adaptors potentiate antibody-based cancer immunotherapy.
Jiang, C T., Chen, K. G., et al.
Nature communications, 2021

Synthesis of TEMPO radical decorated hollow porous aromatic frameworks for selective oxidation of alcohols.
Shen, Yan-Ming, et al.
Chemical Communications, 2021

Measuring particle size distribution and mass concentration of nanoplastics and microplastics: addressing some analytical challenges in the sub-micron size range.
Caputo F, Vogel R, Savage J, et al.
Journal of Colloid and Interface Science, 2021

Considerations for MESF-bead based assignment of absolute fluorescence values to nanoparticles and extracellular vesicles by flow cytometry.
Lozano-Andrés, E., Van Den Broeck，et al.
bioRxiv, 2021

Electrochemical Deposition of Perylene-based Thin Films from Aqueous Solution and Studies of Visible Light-driven Oxidation of Alcohols.
Zhuang J. L Shen, Y M,  et al.
ACS Applied Energy Materials,2020

Sensitive multiplex detection of MicroRNAs based on liquid suspension nano-chip.
Wang X, Yuan W, Xu Y,et al.
Analytica chimica acta,2020

Light-Scattering Detection below the Level of Single Fluorescent Molecules for High-Resolution Characterization of Functional Nanoparticles.
Zhu S, Ma L, Wang S, et al.
ACS Nano, 2014

Progress in the development of techniques based on light scattering for single nanoparticle detection.
Zhu S, Wang S, and Yan X et al.
Science China Chemistry, 2011

Development of an Ultrasensitive Dual-Channel Flow Cytometer for the Individual Analysis of Nanosized Particles and Biomolecules.
Yang L, Zhu S, and Yan X et al.
Analytical Chemistry, 2009

Size Differentiation and Absolute Quantification of Gold Nanoparticles via Single Particle Detection with a Laboratory-Built High-Sensitivity Flow Cytometer.
Zhu S, Yang L, and Yan X et al.
Journal of American Chemical Society, 2010

Rapid and Quantitative Measurement of Single Quantum Dots in a Sheath Flow Cuvette.
Wang S, Li L, and Yan X et al.
Analytical Chemistry, 2017

High-Throughput Single-Nanoparticle Analysis of Metal-Enhanced Fluorescence in Free Solution Using Ag@SiO₂ Core-Shell Nanoparticles.
Yan Y, Meng L, and Yan X et al.
ACS Sensors, 2017

Flow Cytometric Analysis of Nanoscale Biological Particles and Organelles.
Lian H, He S, Chen C, and Yan X.
Annual Review of Analytical Chemistry, 2019

Light-Scattering Sizing of Single Submicron Particles by High-Sensitivity Flow Cytometry.
Zhang W, Tian Y, and Yan X et al.
Analytical Chemistry, 2018

Multiparameter Quantification of Liposomal Nanomedicines at the Single-Particle Level by High-Sensitivity Flow Cytometry.
Yan X, Chen C, Zhu S, Wang S, et al.
ACS Applied Materials and Interfaces, 2017

Nano-Flow Cytometry

Phosphoproteomics identify arachidonic-acid-regulated signal transduction pathways modulating macrophage functions with implications for ovarian cancer.
Dietze, R., Hammoud, M. K., Gomez-Serrano, et al.
Theranostics, 2021

Heparanase from triple‑negative breast cancer and platelets acts as an enhancer of metastasis.
Yang, W. J, Zhang, et al.
International Journal of Oncology, 2020

Electrochemical Deposition of Perylene-based Thin Films from Aqueous Solution and Studies of Visible Light-driven Oxidation of Alcohols.
Zhuang J. L Shen, Y M,  et al.
ACS Applied Energy Materials, 2020

Rapid and Quantitative Measurement of Single Quantum Dots in a Sheath Flow Cuvette.
Wang S, Li L, and Yan X et al.
Analytical Chemistry, 2017

Flow Cytometric Single-Cell Analysis Enables Quantitative in vivo Detection of Protein-Protein Interactions via Relative Reporter Protein Expression Measurement.
Wu L, Wang X, and Yan X et al.
Analytical Chemistry, 2017

High-throughput single-cell analysis of low copy number beta-galactosidase by a laboratory-built high-sensitivity flow cytometer.
Yang L, Huang T, and Yan X et al.
Biosensors & Bioelectronics, 2013

Patents

Caveolin-1蛋白阳性外泌体作为非小细胞肺癌诊断标志物的应用.
郑磊,张涵,安泰学,司徒博,李博
 CN110095604A,2019-08-06.

Preparation of therapeutic exosomes using membrane proteins.
Dooley K. P, Harrison, R A, et al.
U.S. Patent Application No. 16/722,884.

Compositions of engineered exosomes and methods of loading luminal exosomes pay-loads.
McConnell, Russell E., et al.
U.S. Patent Application No. 16/765,116.

Application of the Caveolin-1 protein positive excretion body as Diagnosis of Non-small Cell Lung marker.
Zheng Lei, Zhang Han, An Taixue, Situ Bo, Li Bo.
CN110095604A, 2019-08-06.